Open AccessClinical and Immunological Profiles of 14 Patients With Bullous Pemphigoid Without IgG Autoantibodies to the BP180 NC16A Domain
Author(s) -
Kenta Nakama,
Hiroshi Koga,
Norito Ishii,
Chika Ohata,
Takashi Hashimoto,
Takekuni Nakama
Publication year - 2018
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2017.5465
Subject(s) - medicine , bullous pemphigoid , autoantibody , pemphigoid , antibody , immunoassay , erythema , gastroenterology , immunology
Enzyme-linked immunosorbent assay (ELISA) and/or chemiluminescent enzyme immunoassay (CLEIA) for BP180 noncollagenous 16A (NC16A) extracellular domain is a sensitive diagnostic tool for bullous pemphigoid (BP). However, some patients with BP have negative results for these assays.
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