Association of Thyroid Function Genetic Predictors With Atrial Fibrillation | Zendy

Joe-Élie Salem | Zendy; M. Benjamin Shoemaker | Zendy; Lisa Bastarache | Zendy; Christian M. Shaffer | Zendy; Andrew M. Glazer | Zendy; Brett M. Kroncke | Zendy; Quinn S. Wells | Zendy; Mingjian Shi | Zendy; Péter Straub | Zendy; Gail P. Jarvik | Zendy; Eric B. Larson | Zendy; Digna R. Velez Edwards | Zendy; Todd L. Edwards | Zendy; Lea K. Davis | Zendy; Hákon Hákonarson | Zendy; Chunhua Weng | Zendy; David Fasel | Zendy; Björn C. Knollmann | Zendy; Thomas J. Wang | Zendy; Joshua C. Denny | Zendy; Patrick T. Ellinor | Zendy; Dan M. Roden | Zendy; Jonathan D. Mosley | Zendy

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Association of Thyroid Function Genetic Predictors With Atrial Fibrillation

Author(s) -

Joe-Élie Salem,

M. Benjamin Shoemaker,

Lisa Bastarache,

Christian M. Shaffer,

Andrew M. Glazer,

Brett M. Kroncke,

Quinn S. Wells,

Mingjian Shi,

Péter Straub,

Gail P. Jarvik,

Eric B. Larson,

Digna R. Velez Edwards,

Todd L. Edwards,

Lea K. Davis,

Hákon Hákonarson,

Chunhua Weng,

David Fasel,

Björn C. Knollmann,

Thomas J. Wang,

Joshua C. Denny,

Patrick T. Ellinor,

Dan M. Roden,

Jonathan D. Mosley

Publication year - 2019

Publication title -

jama cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.108

H-Index - 63

eISSN - 2380-6591

pISSN - 2380-6583

DOI - 10.1001/jamacardio.2018.4615

Subject(s) - medicine , thyrotropin receptor , odds ratio , goiter , atrial fibrillation , genetic association , thyroid function , thyroid , genome wide association study , endocrinology , single nucleotide polymorphism , graves' disease , genotype , genetics , biology , gene

Thyroid hormone levels are tightly regulated through feedback inhibition by thyrotropin, produced by the pituitary gland. Hyperthyroidism is overwhelmingly due to thyroid disorders and is well recognized to contribute to a wide spectrum of cardiovascular morbidity, particularly the increasingly common arrhythmia atrial fibrillation (AF).

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