Outpatient Worsening Heart Failure as a Target for Therapy | Zendy

Stephen J. Greene | Zendy; Robert J. Mentz | Zendy; G. Michael Felker | Zendy

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Outpatient Worsening Heart Failure as a Target for Therapy

Author(s) -

Stephen J. Greene,

Robert J. Mentz,

G. Michael Felker

Publication year - 2018

Publication title -

jama cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.108

H-Index - 63

eISSN - 2380-6591

pISSN - 2380-6583

DOI - 10.1001/jamacardio.2017.5250

Subject(s) - medicine , heart failure , intensive care medicine , randomized controlled trial , ambulatory care , clinical trial , outpatient clinic , health care , emergency medicine , economics , economic growth

Hospitalizations for worsening heart failure (WHF) represent an enormous public health and financial burden, with physicians, health systems, and payers placing increasing emphasis on hospitalization prevention. In addition, maximizing time out of the hospital is an important patient-centered outcome. In this review, we discuss the concept of outpatient WHF, highlight the rationale and data for the outpatient treatment of WHF as an alternative to hospitalization, and examine opportunities and strategies for developing outpatient "interceptive" therapies for treatment of worsening symptoms and prevention of hospitalization.

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