Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia
Author(s) -
Clifford R. Jack,
Heather J. Wiste,
Terry M. Therneau,
Stephen D. Weigand,
David S. Knopman,
Michelle M. Mielke,
Val J. Lowe,
Prashanthi Vemuri,
Mary M. Machulda,
Christopher G. Schwarz,
Jeffrey L. Gunter,
Matthew L. Senjem,
Jonathan GraffRadford,
David T. Jones,
Rosebud O. Roberts,
Walter A. Rocca,
Ronald C. Petersen
Publication year - 2019
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2019.7437
Subject(s) - medicine , neurodegeneration , dementia , biomarker , amyloid (mycology) , gerontology , amyloid β , alzheimer's disease , oncology , disease , pathology , genetics , biology
A National Institute on Aging and Alzheimer's Association workgroup proposed a research framework for Alzheimer disease in which biomarker classification of research participants is labeled AT(N) for amyloid, tau, and neurodegeneration biomarkers.
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