Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty | Zendy

Brian F. Gage | Zendy; Anne R. Bass | Zendy; Hannah Lin | Zendy; Scott C. Woller | Zendy; Scott M. Stevens | Zendy; Noor AlHammadi | Zendy; Juan Li | Zendy; Tomás Navarro–Rodriguez | Zendy; J. Philip Miller | Zendy; Gwendolyn A. McMillin | Zendy; Robert C. Pendleton | Zendy; Amir K. Jaffer | Zendy; Cristi R. King | Zendy; Brandi DeVore Whipple | Zendy; Rhonda Porche-Sorbet | Zendy; Lynnae Napoli | Zendy; Kerri Merritt | Zendy; Anna M. Thompson | Zendy; Gina Hyun | Zendy; Jeffrey L. Anderson | Zendy; Wesley Hollomon | Zendy; Robert L. Barrack | Zendy; Ryan M. Nunley | Zendy; Gerard Moskowitz | Zendy; Víctor G. DávilaRomán | Zendy; Charles S. Eby | Zendy

Open Access

Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty

Author(s) -

Brian F. Gage,

Anne R. Bass,

Hannah Lin,

Scott C. Woller,

Scott M. Stevens,

Noor AlHammadi,

Juan Li,

Tomás Navarro–Rodriguez,

J. Philip Miller,

Gwendolyn A. McMillin,

Robert C. Pendleton,

Amir K. Jaffer,

Cristi R. King,

Brandi DeVore Whipple,

Rhonda Porche-Sorbet,

Lynnae Napoli,

Kerri Merritt,

Anna M. Thompson,

Gina Hyun,

Jeffrey L. Anderson,

Wesley Hollomon,

Robert L. Barrack,

Ryan M. Nunley,

Gerard Moskowitz,

Víctor G. DávilaRomán,

Charles S. Eby

Publication year - 2017

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2017.11469

Subject(s) - medicine , warfarin , dosing , randomized controlled trial , vkorc1 , deep vein , adverse effect , arthroplasty , surgery , cyp2c9 , thrombosis , atrial fibrillation , cytochrome p450 , metabolism

Warfarin use accounts for more medication-related emergency department visits among older patients than any other drug. Whether genotype-guided warfarin dosing can prevent these adverse events is unknown.

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