Anti-inflammatory and Analgesic Effects of the Methanol Stem Bark Extract of Brachystegia eurycoma Harms (Fabaceae) | Zendy

Ighodaro Igbe | Zendy

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Anti-inflammatory and Analgesic Effects of the Methanol Stem Bark Extract of Brachystegia eurycoma Harms (Fabaceae)

Author(s) -

Ighodaro Igbe

Publication year - 2012

Publication title -

european journal of medicinal plants

Language(s) - English

Resource type - Journals

ISSN - 2231-0894

DOI - 10.9734/ejmp/2012/1599

Subject(s) - fabaceae , traditional medicine , bark (sound) , analgesic , anti inflammatory , botany , biology , medicine , pharmacology , ecology

Aims: The aim of the study was to investigate the analgesic and anti-inflammatory activities of the methanol stem bark extract of Brachystegia eurycoma Harms. Place and Duration of Study: Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin. Methodology: Analgesic activity was examined using the hot plate and acetic acidinduced writhing test while acute anti-inflammatory effect was studied using carrageenan and dextran-induced paw edema. Results: Oral administration of the extract produced significant (P<0.01) antiedematogenic effect with a dose of 100 mg/kg within the 2 nd

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