EFFECT OF OECOPHYLLA SMARAGDINA ON COMPLETE FREUNDS ADJUVANT INDUCED ARTHRITIS IN ALBINO RAT | Zendy

K. Balamurugan | Zendy; P Natarajan | Zendy

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EFFECT OF OECOPHYLLA SMARAGDINA ON COMPLETE FREUNDS ADJUVANT INDUCED ARTHRITIS IN ALBINO RAT

Author(s) -

K. Balamurugan,

P Natarajan

Publication year - 2018

Publication title -

journal of pharmaceutical and scientific innovation

Language(s) - English

Resource type - Journals

ISSN - 2277-4572

DOI - 10.7897/2277-4572.07495

Subject(s) - biology , zoology

Weaver ant Oecophylla smaragdina (OS) belongs to family Formicidae has been used by traditional village people, and also as the indigenous medicine. The present study was planned to induce rheumatoid arthritis in Wistar albino rats by complete Freund’s adjuvant in the dose of 100μl. The ethanol extract of Oecophylla smaragdina (EEOS) was administered by the oral dose of 200mg/kg, 400mg/kg, for a period of 24 days duration. The Biochemical parameters, haematological parameters, and histopathology of the joint tissue were studied. The Oecophylla smaragdina (OS) extract attenuated the rheumatoid arthritis factors induced by complete Freund’s adjuvant by the dose-dependent manner. The current study concludes that EEOS extract of both concentrations provides a significant effect of anti-arthritic effects.

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