SURGICAL SITE INFECTION DESPITE ANTI-BIOTIC PROPHYLAXIS IN MASTECTOMY: A CASE REPORT

Staphyloc occus aureus is often isolated in surgical site infection (SSI). T he efficacy of prophylactic anti biotic in breast surgery has been addressed in several clinical trials. A 46 - year - old Malay woman with right brea st invasive ductal cancer and a history of ga stritis for six years was admitted for right modified radical mastectomy wi th axillary clearance level II. Axillary drain had been continued for more than one week. T wo days after the mastectomy, t he patient presented with pus collection with haemoserrous discharge, despite treatment with Augmentin . Dressing was not soaked. Pus swab culture revealed Staphylococcus aureus sensitive to Cloxacillin, Erythromyci n, Cotrimazole and Fusidic acid and resistant to Penicillin G . Tablet C loxacillin 500 mg was given fo ur times a day for wound infection. Appropriate selection of prophylactic antibiot ic is important to reduce risk of infection . K eywords: Cloxacillin, Erythromyci n, Cotrimazole , Fusidic acid