A PHARMACEUTICAL APPROACH OF MANIKYA BHASMA TOWARDS ITS STANDARDIZATION

Manikya [ Ruby ] is one of the nine gems desc ribed in Ayurveda texts comprising of Aluminum oxide, chromium and Titanium. Manikya Bhasma [MB] is one of the exceptional preparations mentioned in Rasashastra texts . It is having innovate action on various hormonal, enzymatic, immunological pathways, as it com prises main stream trace elemental moieties. The Objective of the study was to prepare MB and standardize it with different physico - chemical parameters . Two types of Manikya bhasma were prepared i.e. Hartaladi Manikya Bhasma [MB1] and Vanaspati (gulab jal marit) Manikya Bhasma [ MB2 ] as per textual reference with the help of 8 puta (ancient heating proce dure ). Prepared bhasma was subjected to ancient as well as modern physico - chemical analysis mainly XRD, DLS, Microscopic examination and results were compare d. XRD Result of Raw Ruby showed Al 2 O 3 as principal component . Mean Particle Size of Raw Ruby is 1 071.58 nm . The particle size s of MB1 and MB2 were respectively 43 n m and 63 nm. So it can be concluded that both MB1 and MB2 are nano medicine, hence both wil l have better assimilation in human body .