Open AccessULTRASOUND PROMOTED ONE POT SYNTHESIS OF 1,5-BENZOTHIAZEPINES USING POLYETHYLENE GLYCOL (PEG-400)
Author(s) -
Chandrashekhar G Devkate,
S. Kola,
Digambar D. Gaikwad,
Mohammad Idrees M Siddique
Publication year - 2018
Publication title -
international research journal of pharmacy
Language(s) - English
Resource type - Journals
ISSN - 2230-8407
DOI - 10.7897/2230-8407.0911280
Subject(s) - polyethylene glycol , peg ratio , ultrasound , chemistry , nuclear chemistry , medicine , organic chemistry , business , radiology , finance
Synthesis of a variety of 1,5-benzothiazepines using polyethylene glycol PEG-400 as a medium and promoter. The synthesis is carried out using ultrasonic irradiation. The advantage of this protocol is that it eco-friendly, mild reaction conditions and the synthesis highlights the use of ultrasound irradiation.
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