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Synthesis of a variety of 1,5-benzothiazepines using polyethylene glycol PEG-400 as a medium and promoter. The synthesis is carried out using ultrasonic irradiation. The advantage of this protocol is that it eco-friendly, mild reaction conditions and the synthesis highlights the use of ultrasound irradiation.

ULTRASOUND PROMOTED ONE POT SYNTHESIS OF 1,5-BENZOTHIAZEPINES USING POLYETHYLENE GLYCOL (PEG-400)