Autoimmune inflammatory neuropathy.

Autoimmune inflammatory neuropathy is a spectrum of disorders: acute and chronic focal and generalised demyelinating and axonal Guillain-Barre syndrome: reflexes, cerebrospinal fluid and neurophysiology may be normal in the early stages adverse prognostic factors: older age, preceding diarrhoea, severe weakness, inexcitable nerves treat with intravenous immunoglobulin Chronic demyelinating neuropathy: check for a paraprotein IgM κ paraprotein with antibodies to myelin-associated glycoprotein is associated with a benign, predominantly sensory neuropathy treat chronic inflammatory demyelinating polyradiculoneuropathy initially with prednisolone or intravenous immunoglobulin treat multifocal motor neuropathy with conduction block with intravenous immunoglobulin.