Implementing a Protocol to Optimize Detection of Chromosome Abnormalities in Cases of Miscarriage or Stillbirth at a Midwestern Teaching Hospital | Zendy

Shobana Kubendran | Zendy; Jennifer Duong | Zendy; Fanglong Dong | Zendy; Amy Lueking | Zendy; Darren Farley | Zendy

Open Access

Implementing a Protocol to Optimize Detection of Chromosome Abnormalities in Cases of Miscarriage or Stillbirth at a Midwestern Teaching Hospital

Author(s) -

Shobana Kubendran,

Jennifer Duong,

Fanglong Dong,

Amy Lueking,

Darren Farley

Publication year - 2018

Publication title -

the permanente journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.445

H-Index - 30

eISSN - 1552-5775

pISSN - 1552-5767

DOI - 10.7812/tpp/17-204

Subject(s) - medicine , miscarriage , genetic testing , indeterminate , abortion , protocol (science) , microarray , genetic counseling , obstetrics , pregnancy , genetics , pathology , biology , gene , gene expression , alternative medicine , mathematics , pure mathematics

Results from chromosome testing after spontaneous abortion (SAB) or intrauterine fetal demise (IUFD) are useful in patient counseling; however, results can be inconclusive when cell cultures for chromosomes are unable to grow from products of conception. Chromosomal microarray analysis (CMA) can analyze DNA from nonviable fetal tissue.

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