Glioblastoma Multiforme in a Patient with Multiple Myeloma: A Case Report and Literature Review
Author(s) -
Christine Moore,
Moayed Ibrahim,
Aaysha Kapila,
Kailash Bajaj
Publication year - 2018
Publication title -
the permanente journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.445
H-Index - 30
eISSN - 1552-5775
pISSN - 1552-5767
DOI - 10.7812/tpp/17-125
Subject(s) - lenalidomide , medicine , multiple myeloma , thalidomide , oncology , myelodysplastic syndromes , nausea , dermatology , bone marrow
Lenalidomide is an immunomodulatory drug approved by the US Food and Drug Administration in 2006 for the treatment of multiple myeloma. In 2012, the Food and Drug Administration issued a statement warning physicians of the increased risk with lenalidomide treatment of the following secondary primary malignancies: Acute myelogenous leukemia, myelodysplastic syndromes, and Hodgkin lymphoma. The statement did not mention glioblastoma multiforme, a Grade 4 astrocytoma, or other high-grade astrocytomas that have been reported on rare occasions in the setting of multiple myeloma.
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