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“Getting off the Bus Closer to Your Destination”: Patients’ Views about Pharmacogenetic Testing
Author(s) -
Susan Brown Trinidad,
Tara B. Coffin,
Stephanie M. Fullerton,
James D. Ralston,
Gail P. Jarvik,
Eric B. Larson
Publication year - 2015
Publication title -
the permanente journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.445
H-Index - 30
eISSN - 1552-5775
pISSN - 1552-5767
DOI - 10.7812/tpp/15-046
Subject(s) - medicine , denial , focus group , pharmacogenetics , carbamazepine , focus (optics) , medical diagnosis , psychiatry , family medicine , psychotherapist , psychology , pathology , epilepsy , genetics , gene , physics , marketing , biology , genotype , optics , business
The authors conducted focus groups with patients prescribed antidepressants (pilot session plus 2 focus groups, n = 27); patients prescribed carbamazepine (2 focus groups, n = 17); and healthy patients (2 focus groups, n = 17). Although participants understood the potential advantages of pharmacogenetic testing, many felt that the risks (discrimination, stigmatization, physician overreliance on genomic results, and denial of certain medications) may outweigh the benefits. These concerns were shared across groups but were more strongly expressed among participants with chronic mental health diagnoses.

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