Obstetric and perinatal outcomes of dizygotic twin pregnancies resulting from in vitro fertilization versus spontaneous conception: a retrospective study | Zendy

Chen Hua | Zendy; Ying Wan | Zendy; Haitao Xi | Zendy; Weijue Su | Zendy; Jing Cheng | Zendy; Chunfang Zhu | Zendy; Jieqiang Lv | Zendy; Xinmei Wu | Zendy; Junzhao Zhao | Zendy

Open Access

Obstetric and perinatal outcomes of dizygotic twin pregnancies resulting from in vitro fertilization versus spontaneous conception: a retrospective study

Author(s) -

Chen Hua,

Ying Wan,

Haitao Xi,

Weijue Su,

Jing Cheng,

Chunfang Zhu,

Jieqiang Lv,

Xinmei Wu,

Junzhao Zhao

Publication year - 2019

Publication title -

peerj

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.927

H-Index - 70

ISSN - 2167-8359

DOI - 10.7717/peerj.6638

Subject(s) - dizygotic twins , obstetrics , in vitro fertilisation , medicine , twin pregnancy , spontaneous conception , assisted reproductive technology , multiple birth , pregnancy , dizygotic twin , gynecology , reproductive technology , retrospective cohort study , fetus , infertility , twin study , population , biology , genetics , environmental health , lactation , heritability

This study was designed to to assess perinatal and neonatal outcomes of dizygotic twin pregnancies conceived naturally or by in vitro fertilization (IVF). After strict selection, the study included 470 dizygotic twin pregnancies. There were 249 resulting from IVF treatments and 221 conceiving spontaneously. After adjusting maternal age and primiparity, the results showed that there were no significant differences between the two groups ( P > 0.05) in terms of maternal antenatal complications and neonatal outcomes. In conclusion, our study does not reveal increased risks for pregnancy-related complications and adverse neonatal outcomes in dizygotic twin pregnancies following IVF treatments. With these fundamental data, this study could provide a reference for perinatal care and clinical assisted reproductive technology (ART) treatment and help to inform infertile parents about the potential risks of IVF treatments.

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