Detection of aYersinia pestisgene homologue in rodent samples | Zendy

Timothy A. Giles | Zendy; Alex D. Greenwood | Zendy; Kyriakos Tsangaras | Zendy; Tom Giles | Zendy; Paul Barrow | Zendy; D. Hannant | Zendy; Abu-Bakr Abu-Median | Zendy; Lisa Yon | Zendy

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Detection of aYersinia pestisgene homologue in rodent samples

Author(s) -

Timothy A. Giles,

Alex D. Greenwood,

Kyriakos Tsangaras,

Tom Giles,

Paul Barrow,

D. Hannant,

Abu-Bakr Abu-Median,

Lisa Yon

Publication year - 2016

Publication title -

peerj

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.927

H-Index - 70

ISSN - 2167-8359

DOI - 10.7717/peerj.2216

Subject(s) - yersinia pestis , rodent , biology , gene , yersinia , genetics , microbiology and biotechnology , bacteria , virulence , ecology

A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat ( Rattus rattus and Rattus norvegicus ) and of mice ( Mus musculus and Apodemus sylvaticus ) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker.

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