Contribution of neutrophils in the pathogenesis of rheumatoid arthritis | Zendy

Lingshu Zhang | Zendy; Yi Yuan | Zendy; Qiang Xu | Zendy; Zhengyu Jiang | Zendy; CongQiu Chu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Contribution of neutrophils in the pathogenesis of rheumatoid arthritis

Author(s) -

Lingshu Zhang,

Yi Yuan,

Qiang Xu,

Zhengyu Jiang,

CongQiu Chu

Publication year - 2020

Publication title -

journal of biomedical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.617

H-Index - 31

eISSN - 2352-4685

pISSN - 1674-8301

DOI - 10.7555/jbr.33.20190075

Subject(s) - neutrophil extracellular traps , immunology , rheumatoid arthritis , pathogenesis , effector , innate immune system , immune system , arthritis , medicine , biology , inflammation

Neutrophils are major innate immune effector cells for host defense and have been a topic of active research for their participation in the pathogenesis of autoimmune inflammatory diseases including rheumatoid arthritis (RA) due to recently discovered neutrophil extracellular trap (NET) formation. NET formation and other mechanisms leading to the release of neutrophil nuclear and cytoplasmic contents are implicated as a source of citrullinated antigens in RA. Further investigations are required to delineate what factors diverge neutrophils from host defense to autoimmune response in RA.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research