Biclonal Gammopathy of IgA Kappa variants - A Case Report | Zendy

Manchana Lakshman Kumar | Zendy; Mahjabeen Salma | Zendy; P. Bhulaxmi | Zendy; K. Malathi | Zendy; Shaik Karimuddin Abdullah | Zendy

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Biclonal Gammopathy of IgA Kappa variants - A Case Report

Author(s) -

Manchana Lakshman Kumar,

Mahjabeen Salma,

P. Bhulaxmi,

K. Malathi,

Shaik Karimuddin Abdullah

Publication year - 2014

Publication title -

international journal of biomedical research

Language(s) - English

Resource type - Journals

eISSN - 2455-0566

pISSN - 0976-9633

DOI - 10.7439/ijbr.v5i10.795

Subject(s) - medicine , kappa , monoclonal gammopathy , dermatology , gammopathy , pathology , antibody , immunology , philosophy , linguistics , monoclonal , monoclonal antibody

Multiple myeloma is a clonal malignant neoplasm of plasma cells and is characterized by the secretion of monoclonal protein in plasma. Here, we report a case of biclonal multiple myeloma having two spikes on serum protein electrophoresis, one being in Beta-2 region and the other in gamma region. Further on immunofixation, both peaks were found to be of IgA-kappa variant. Biclonal gammopathy is a rare case, which accounts for only 1% of all myelomas but biclonal gammopathy of IgA kappa variant has not been described in the literature so far.

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