CRYOTHERAPY AS A MODALITY FOR TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA | Zendy

Naina Kumar | Zendy

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CRYOTHERAPY AS A MODALITY FOR TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA

Author(s) -

Naina Kumar

Publication year - 2012

Publication title -

international journal of biomedical and advance research

Language(s) - English

Resource type - Journals

eISSN - 2455-0558

pISSN - 2229-3809

DOI - 10.7439/ijbar.v3i11.259

Subject(s) - cryotherapy , cervical intraepithelial neoplasia , modality (human–computer interaction) , medicine , treatment modality , intraepithelial neoplasia , dermatology , cervical cancer , radiology , cancer , computer science , prostate , human–computer interaction

ABSTRACT

Aim: The study was done to determine the effectiveness of Cryotherapy in treatment of cervical intraepithelial neoplasia I,II and III.

Background: Cryotherapy is a time proven ablative method of treating lower grades of cervical dysplasia. It is done using compressed CO2 or N2O refrigerant with the aim of creating an ice ball with a depth of freeze denoted by a peripheral margin of 4-5 mm of frost. It is performed using a double freeze or single freeze technique. Currently the double freeze technique of cryotherapy is an accepted treatment for mild and focal moderate dysplasia of the uterine cervix.

Material and Methods: A clinical observational study was undertaken at a tertiary care teaching hospital on 30 selected patients from the outpatient department of Obstetrics and Gynaecology over a period of 3 years.

Results: Overall clinical improvement following cryotherapy was seen in 67.43%. Cure rates in CIN I was 80.9%, in CIN II 71.4% and in CIN III 50.0%.

Conclusion: Cryosurgery is an effective treatment of cervical lesions with negligible side effects or minor complications. It is the most favoured ablative technique for treatment of lower grades of cervical intraepithelial neoplasia like CIN I and CIN II.

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