MicroRNAs and Metastasis-related Gene Expression in Egyptian Breast Cancer Patients | Zendy

Mohamed M. Hafez | Zendy; Zeinab Hassan | Zendy; AbdelRahman N. Zekri | Zendy; Ayman Gaber | Zendy; Salem S. Al Rejaie | Zendy; Mohamed M. SayedAhmed | Zendy; Othman Al Shabanah | Zendy

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MicroRNAs and Metastasis-related Gene Expression in Egyptian Breast Cancer Patients

Author(s) -

Mohamed M. Hafez,

Zeinab Hassan,

AbdelRahman N. Zekri,

Ayman Gaber,

Salem S. Al Rejaie,

Mohamed M. SayedAhmed,

Othman Al Shabanah

Publication year - 2012

Publication title -

asian pacific journal of cancer prevention

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.512

H-Index - 75

eISSN - 2476-762X

pISSN - 1513-7368

DOI - 10.7314/apjcp.2012.13.2.591

Subject(s) - microrna , mmp2 , breast cancer , cancer research , metastasis , biology , mmp9 , gene , regulation of gene expression , oncogene , gene expression , pten , cancer , downregulation and upregulation , oncology , apoptosis , medicine , cell cycle , genetics , pi3k/akt/mtor pathway

MicroRNAs (miRNAs) are a class of naturally occurring small noncoding RNAs that regulate gene expression, cell growth, differentiation and apoptosis by targeting mRNAs for translational repression or cleavage. The present study was conducted to study miRNAs in Egyptian breast cancer (BC) and their relation to metastasis, tumor invasion and apoptosis in addition to their association with the ER and PR statuses.

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