HiF-1α siRNA and Cisplatin in Combination SuppressTumor Growth in a Nude Mice Model of Esophageal Squamous Cell Carcinoma
Author(s) -
Hongying Liao,
Guiping Wang,
Lijia Gu,
Shaohong Huang,
Xiuling Chen,
Yun Li,
Songwang Cai
Publication year - 2012
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2012.13.2.473
Subject(s) - cisplatin , esophageal squamous cell carcinoma , basal cell , cancer research , oncology , carcinoma , medicine , chemotherapy
The esophagus squamous cell carcinoma (ESCC) is one of the most deadly malignances, and a current challenge is the development of effective therapeutic agents. Our present work addressed the effect of HIF-1α siRNA alone or in combination with cisplatin on the growth of ESCC in nude mice.
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