Analysis of K-ras codon 12 and TP53 mutations in patients with advanced colorectal carcinoma | Zendy

Gulnur Zhunussova | Zendy; Leyla Djansugurova | Zendy; Elmira Khussainova | Zendy; Benazir Zhunusbekova | Zendy; Georgiy Afonin | Zendy; Д. К. Хайдарова | Zendy; Marco Matejcic | Zendy; M. Iqbal Parker | Zendy

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Analysis of K-ras codon 12 and TP53 mutations in patients with advanced colorectal carcinoma

Author(s) -

Gulnur Zhunussova,

Leyla Djansugurova,

Elmira Khussainova,

Benazir Zhunusbekova,

Georgiy Afonin,

Д. К. Хайдарова,

Marco Matejcic,

M. Iqbal Parker

Publication year - 2015

Publication title -

south african medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.527

H-Index - 57

eISSN - 2078-5135

pISSN - 0256-9574

DOI - 10.7196/samjnew.7886

Subject(s) - colorectal cancer , exon , medicine , genetics , intron , mutation , coding region , carcinoma , polymerase chain reaction , gene , cancer research , microbiology and biotechnology , cancer , biology

Colorectal cancer (CRC) is one of the most common types of cancer, affecting 3 - 5% of the global population. K-ras protooncogene and TP53 tumour suppressor gene mutations are among the most common genetic alterations detected in advanced colorectal tumours.

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