Effect of myomectomy on endometrial glutathione peroxidase 3 (GPx3) and glycodelin mRNA expression at the time of the implantation window.
Author(s) -
Marzieh Farimani Sanoee,
Tahereh Alizamir,
Shamila Faramarzi,
Massoud Saidijam,
Reza Yadegarazari,
Nooshin Shabab,
Alireza Rastgoo Haghi,
Zohreh Alizadeh
Publication year - 2014
Publication title -
pubmed
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 31
ISSN - 2008-823X
DOI - 10.6091/ibj.1222.2013
Subject(s) - gpx3 , endometrium , andrology , gene expression , gpx1 , gene , real time polymerase chain reaction , luteal phase , menstrual cycle , glutathione peroxidase , biology , medicine , gynecology , endocrinology , glutathione , hormone , enzyme , genetics , biochemistry
In fertile women, glycodelin and glutathione peroxidase 3 (GPx3) genes expression rises during the luteal phase, with a peak occurring during the implantation window. The expression of these genes decreases in women with myomas. To determine whether myomectomy would reverse glycodelin and GPx3 expression, we evaluated the transcript levels of these genes in the endometrium of patients before and after myomectomy.
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