Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion | Zendy

Alex B. Lentsch | Zendy

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Regulatory Mechanisms of Injury and Repair after Hepatic Ischemia/Reperfusion

Author(s) -

Alex B. Lentsch

Publication year - 2012

Publication title -

scientifica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.474

H-Index - 21

ISSN - 2090-908X

DOI - 10.6064/2012/513192

Subject(s) - ischemia , reperfusion injury , liver transplantation , medicine , warm ischemia , complication , parenchyma , liver injury , orthotopic liver transplantation , transplantation , surgery , cardiology , pathology

Hepatic ischemia/reperfusion injury is an important complication of liver surgery and transplantation. The mechanisms of this injury as well as the subsequent reparative and regenerative processes have been the subject of thorough study. In this paper, we discuss the complex and coordinated responses leading to parenchymal damage after liver ischemia/reperfusion as well as the manner in which the liver clears damaged cells and regenerates functional mass.

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