Open AccessThe Effect of Platelet‐Rich Plasma in Hair Regrowth: A Randomized Placebo‐Controlled Trial
Author(s) -
Gentile Pietro,
Garcovich Simone,
Bielli Alessandra,
Scioli Maria Giovanna,
Orlandi Augusto,
Cervelli Valerio
Publication year - 2015
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2015-0107
Subject(s) - platelet rich plasma , placebo , hair loss , medicine , itching , hair follicle , randomized controlled trial , urology , surgery , platelet , dermatology , pathology , alternative medicine
Platelet‐rich plasma (PRP) as a treatment for male pattern hair loss was investigated in a randomized, placebo‐controlled study in which 20 men received PRP on half of their scalp and placebo on the other. Patients received 3 treatments at 30‐day intervals. Hair regrowth was quantified by a blinded evaluator using computerized trichograms. Patients were followed for 2 years; study endpoints were hair regrowth, hair dystrophy as measured by dermoscopy, burning or itching sensation, and cell proliferation as measured by Ki‐67 evaluation. At the end of three treatment cycles, clinical improvement was seen in several parameters. Four of 20 patients experience continued hair loss and required retreatment.