Robust Differentiation of mRNA‐Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage | Zendy

Sridhar Akshayalakshmi | Zendy; Ohlemacher Sarah K. | Zendy; Langer Kirstin B. | Zendy; Meyer Jason S. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Robust Differentiation of mRNA‐Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage

Author(s) -

Sridhar Akshayalakshmi,

Ohlemacher Sarah K.,

Langer Kirstin B.,

Meyer Jason S.

Publication year - 2016

Publication title -

stem cells translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.781

H-Index - 71

eISSN - 2157-6580

pISSN - 2157-6564

DOI - 10.5966/sctm.2015-0093

Subject(s) - reprogramming , induced pluripotent stem cell , biology , microbiology and biotechnology , cellular differentiation , stem cell , regenerative medicine , cell fate determination , genetics , cell , embryonic stem cell , gene , transcription factor

The ability and efficiency of mRNA‐reprogrammed human induced pluripotent stem cells (hiPSCs) to yield retinal cell types in a directed, stepwise manner was tested. hiPSCs derived through mRNA‐based reprogramming strategies offer numerous advantages owing to the lack of genomic integration or constitutive expression of pluripotency genes. Such methods represent a promising new approach for retinal stem cell research, especially translational applications.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research