Open AccessEnabling Consistency in Pluripotent Stem Cell‐Derived Products for Research and Development and Clinical Applications Through Material Standards
Author(s) -
French Anna,
Bravery Christopher,
Smith James,
Chandra Amit,
Archibald Peter,
Gold Joseph D.,
Artzi Natalie,
Kim Hae-Won,
Barker Richard W.,
Meissner Alexander,
Wu Joseph C.,
Knowles Jonathan C.,
Williams David,
García-Cardeña Guillermo,
Sipp Doug,
Oh Steve,
Loring Jeanne F.,
Rao Mahendra S.,
Reeve Brock,
Wall Ivan,
Carr Andrew J.,
Bure Kim,
Stacey Glyn,
Karp Jeffrey M.,
Snyder Evan Y.,
Brindley David A.
Publication year - 2015
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2014-0233
Subject(s) - induced pluripotent stem cell , consistency (knowledge bases) , computer science , population , product (mathematics) , microbiology and biotechnology , risk analysis (engineering) , biochemical engineering , computational biology , biology , medicine , embryonic stem cell , engineering , mathematics , artificial intelligence , genetics , geometry , environmental health , gene
This article discusses the need for reference materials, potential challenges faced by human pluripotent stem cell‐derived products, and possible approaches to alleviating concerns about consistency and reproducibility in their production. It is hoped that the research community and tool providers will engage to assess and incorporate into practice potential approaches, as appropriate, and that novel thinking will lead to approaches that more satisfactorily fulfill the needs outlined.