Open AccessIntrastriatal Transplantation of Adult Human Neural Crest‐Derived Stem Cells Improves Functional Outcome in Parkinsonian Rats
Author(s) -
Müller Janine,
Ossig Christiana,
Greiner Johannes F.W.,
Hauser Stefan,
Fauser Mareike,
Widera Darius,
Kaltschmidt Christian,
Storch Alexander,
Kaltschmidt Barbara
Publication year - 2015
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2014-0078
Subject(s) - neuroscience , induced pluripotent stem cell , transplantation , stem cell , substantia nigra , embryonic stem cell , neural stem cell , dopaminergic , regenerative medicine , biology , medicine , dopamine , microbiology and biotechnology , biochemistry , gene
The present study investigated the potential of adult human neural crest‐derived stem cells derived from the inferior turbinate (ITSCs) transplanted into a parkinsonian rat model. The research demonstrated that adult human ITSCs are capable of functionally recovering a rat model of Parkinson's disease.