Open AccessConcise Review: Mesenchymal Stromal Cells Used for Periodontal Regeneration: A Systematic Review
Author(s) -
Monsarrat Paul,
Vergnes Jean-Noël,
Nabet Cathy,
Sixou Michel,
Snead Malcolm L.,
Planat-Bénard Valérie,
Casteilla Louis,
Kémoun Philippe
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0183
Subject(s) - mesenchymal stem cell , regeneration (biology) , stromal cell , computational biology , microbiology and biotechnology , biology , chemistry , cancer research
This systematic review provided good evidence of the capacity of mesenchymal stromal cells to regenerate periodontal tissues in animals; however, experimentally generated defects used in animal studies do not sufficiently mimic the pathophysiology of periodontitis in humans. Moreover, the safety of such interventions in humans still needs to be studied.