Open AccessAdipose‐Derived Cell Construct Stabilizes Heart Function and Increases Microvascular Perfusion in an Established Infarct
Author(s) -
LeBlanc Amanda J.,
Nguyen Quang T.,
Touroo Jeremy S.,
Aird Allison L.,
Chang Raymond C.,
Ng Chin K.,
Hoying James B.,
Williams Stuart K.
Publication year - 2013
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0046
Subject(s) - perfusion , adipose tissue , cardiology , cell , function (biology) , medicine , chemistry , microbiology and biotechnology , biology , biochemistry
This study investigated the cardiac recovery potential of a stromal vascular fraction (SVF) construct implanted onto an established infarct. Findings suggest that SVF treatment of an established infarct stabilizes the heart at the time point of intervention by preventing a worsening of cardiac performance and infarcted volume and increasing perfusion of the microcirculation.