Open AccessConcise Review: Immunologic Lessons From Solid Organ Transplantation for Stem Cell‐Based Therapies
Author(s) -
Loewendorf Andrea,
Csete Marie
Publication year - 2013
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2012-0125
Subject(s) - allorecognition , transplantation , immune system , organ transplantation , stem cell , immunology , biology , graft rejection , medicine , t cell , microbiology and biotechnology
This article reviews current understanding of selected topics in transplant immunology that have not been prominent in the stem cell literature, including immune responses to ischemia/reperfusion injuries, natural killer cells, the adaptive immune response, some unresolved issues in T‐cell allorecognition, costimulatory molecules, and the anticipated role of regulatory T cells in graft tolerance.