Concise Review: Immunologic Lessons From Solid Organ Transplantation for Stem Cell‐Based Therapies | Zendy

Loewendorf Andrea | Zendy; Csete Marie | Zendy

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Concise Review: Immunologic Lessons From Solid Organ Transplantation for Stem Cell‐Based Therapies

Author(s) -

Loewendorf Andrea,

Csete Marie

Publication year - 2013

Publication title -

stem cells translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.781

H-Index - 71

eISSN - 2157-6580

pISSN - 2157-6564

DOI - 10.5966/sctm.2012-0125

Subject(s) - allorecognition , transplantation , immune system , organ transplantation , stem cell , immunology , biology , graft rejection , medicine , t cell , microbiology and biotechnology

This article reviews current understanding of selected topics in transplant immunology that have not been prominent in the stem cell literature, including immune responses to ischemia/reperfusion injuries, natural killer cells, the adaptive immune response, some unresolved issues in T‐cell allorecognition, costimulatory molecules, and the anticipated role of regulatory T cells in graft tolerance.

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