Open AccessConcise Review: Cell Therapy and Tissue Engineering for Cardiovascular Disease
Author(s) -
Haraguchi Yuji,
Shimizu Tatsuya,
Yamato Masayuki,
Okano Teruo
Publication year - 2012
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2012-0030
Subject(s) - regenerative medicine , cell therapy , medicine , disease , clinical trial , tissue engineering , cell , bioinformatics , intensive care medicine , pathology , biology , biomedical engineering , genetics
Cardiovascular disease is a major cause of morbidity and mortality, especially in developed countries. Various therapies for cardiovascular disease are investigated actively and are performed clinically. Recently, cell‐based regenerative medicine using several cell sources has appeared as an alternative therapy for curing cardiovascular diseases. Scaffold‐based or cell sheet‐based tissue engineering is focused as a new generational cell‐based regenerative therapy, and the clinical trials have also been started. Cell‐based regenerative therapies have an enormous potential for treating cardiovascular disease. This review summarizes the recent research of cell sources and cell‐based‐regenerative therapies for cardiovascular diseases.