Cardiac Sympathetic Hyperactivity after Chemotherapy: Early Sign of Cardiotoxicity? | Zendy

Sarita Lígia Pessoa de Melo Machado Guimarães | Zendy; Simone Cristina Soares Brandão | Zendy; Luciana Raposo Andrade | Zendy; Rafael José Coelho Maia | Zendy; Brivaldo Markman Filho | Zendy

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Cardiac Sympathetic Hyperactivity after Chemotherapy: Early Sign of Cardiotoxicity?

Author(s) -

Sarita Lígia Pessoa de Melo Machado Guimarães,

Simone Cristina Soares Brandão,

Luciana Raposo Andrade,

Rafael José Coelho Maia,

Brivaldo Markman Filho

Publication year - 2015

Publication title -

arquivos brasileiros de cardiologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.4

H-Index - 53

eISSN - 1678-4170

pISSN - 0066-782X

DOI - 10.5935/abc.20150075

Subject(s) - medicine , cardiotoxicity , ejection fraction , anthracycline , chemotherapy , breast cancer , cardiology , mediastinum , washout , heart rate , heart failure , cancer , radiology , blood pressure

Chemotherapy with anthracyclines and trastuzumab can cause cardiotoxicity. Alteration of cardiac adrenergic function assessed by metaiodobenzylguanidine labeled with iodine-123 (123I-mIBG) seems to precede the drop in left ventricular ejection fraction.

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