Open AccessPHYTOCHEMICAL INVESTIGATION OFWissadula periplocifolia(L.) C. Presl AND EVALUATION OF ITS ANTIBACTERIAL ACTIVITY
Author(s) -
Yanna Carolina Ferreira Teles,
Roosevelt Albuquerque Gomes,
Micaelly da Silva Oliveira,
Kaio L. de Lucena,
José Soares do Nascimento,
Maria de Fátima Agra,
John O. Igoli,
Alexander I. Gray,
María de Fátima Vanderlei de Souza
Publication year - 2014
Publication title -
química nova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.214
H-Index - 73
eISSN - 1678-7064
pISSN - 0100-4042
DOI - 10.5935/0100-4042.20140238
Subject(s) - phytochemical , traditional medicine , antibacterial activity , chemistry , biology , medicine , bacteria , genetics
A phytochemical study on the aerial parts of Wissadula periplocifolia using chromatographic techniques has led to the isolation of sitosterol (1a), stigmasterol (1b), sitosterol 3-O-β-D-glucopyranoside (2a), stigmasterol 3-O-β-D-glucopyranoside (2b), phaeophytin A (3), 13²-hydroxy-(13²-S)-phaeophytin A (4), phaeophytin B (5), 17³-ethoxyphaeophorbide (6), 3,4-seco-urs-4(23),20(30)-dien-3-oic acid (7), 3-oxo-21β-H-hop-22(29)-ene (8), dammaradienone (9a), and taraxastenone (9b). The isolated compounds were characterised by spectroscopic analysis. A preliminary assay to evaluate the antibacterial activity of W. periplocifolia extracts and fractions showed that the dichloromethane, ethyl acetate, and n-butanol fractions were active against Enterococcus faecalis
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