Isoliquiritigenin and -sitosterol from Cissus polyantha Tuber Glig and Brandt

Chemical investigation into the composition of Cissus polyantha tuber, a plant used in Northern Nigerian ethno medicine for managing inflammatory conditions and conjunctivitis has led to the isolation of a chalcone from the ethyl acetate and a steroid from the hexane soluble fractions of its methanol extract. The structures of these compounds were elucidated by extensive analysis of their spectroscopic data, including 1 and 2D nuclear magnetic resonance (NMR). This is the first report of the isolation of the compounds from the plant and they may be responsible for the previously reported antiinflammatory effects.