Isolation and spectral characterization of a new biaurone from Pongamia pinnata (L.) Pierre. (Fabaceae) pods | Zendy

Pramod Kumar | Zendy; Kumar Munesh | Zendy; W Bussman Rainer | Zendy

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Isolation and spectral characterization of a new biaurone from Pongamia pinnata (L.) Pierre. (Fabaceae) pods

Author(s) -

Pramod Kumar,

Kumar Munesh,

W Bussman Rainer

Publication year - 2012

Publication title -

journal of medicinal plants research

Language(s) - English

Resource type - Journals

ISSN - 1996-0875

DOI - 10.5897/jmpr11.1300

Subject(s) - pongamia , fabaceae , traditional medicine , column chromatography , chemistry , chloroform , organic chemistry , botany , medicine , biology , biodiesel , catalysis

Pongamia pinnata (L.) Pierre. (Fabaceae) locally known as karanja is widely used to treat rheumatic pains, hypertension, bronchitis, whooping cough, and skin diseases. The present study attempts to isolate new compounds from a methanolic extract of P. pinnata pods. A novel light green, amorphous, powdered compound has been isolated from chloroform: methanol ratio (8.2:1.8) eluent through column chromatography, and is named pongamiabiaurone. The molecular weight of the new compound was determined as 716 by electron impact mass spectroscopy. Through a combination of 1HNMR and 13CNMR spectral analysis, the structure of pongamiabiaurone was confirmed as 3-tetradecanoxy-4’-methoxy auronyl (13→13)-3’hydroxy-4’-methoxyaurone. Key words: Methanolic extract, Pongamia pinnata, streptozotocin, diabetes mellitus.

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