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Tamarixetin and kaempferide were considered as the major active constituents of Tamarix chinensis, and had several known bioactivities. An effective and inexpensive high-performance liquid chromatographic method was established and validated for the determination of tamarixetin and kaempferide in rat tissues following a single oral administration. Tissue distribution showed the highest level of tamarixetin was observed in lung, then in heart; and the highest concentration of kaempferide was determined in heart.   Key words: Liquid chromatography, tissues distribution, tamarixetin, kaempferide.

Detection of tamarixetin and kaempferide in different tissues by high-performance liquid chromatography in tamarixetin and kaempferide treated rats