Fast identification of flavonoids in the roots of Sophora flavescens by on-flow LC-NMR
Author(s) -
Jin Kim Su,
Min Sang,
Cheol Kim Min,
Woo Kang Suk,
Hun Um Byung
Publication year - 2010
Publication title -
journal of medicinal plants research
Language(s) - English
Resource type - Journals
ISSN - 1996-0875
DOI - 10.5897/jmpr10.073
Subject(s) - sophora flavescens , sophora , chemistry , chromatography , flavonoid , two dimensional nuclear magnetic resonance spectroscopy , traditional medicine , radix (gastropod) , stereochemistry , traditional chinese medicine , botany , organic chemistry , biology , medicine , matrine , alternative medicine , pathology , antioxidant
Sophora flavescens Ait (Leguminosae) is a Chinese herbal medicine. Sophorae radix, the dried roots of S. flavescens, has been used for various diseases including atherosclerosis and arrhythmias. For the direct identification of the compounds present in Sophorae radix, the hyphenated LC-NMR technique has been applied. WET solvent suppression and scout scan techniques were used to suppress solvent peaks in on-flow LC-NMR experiment. Six prenylflavonoids were identified successfully as kushenol U (1), kurarinone (2), sophoraflavanone G (3), leachianone A (4), kuraridin (5) and kushenol A (6). Key words: LC-hyphenated, on-flow LC-NMR, prenyl-flavonoid, Sophora flavescens.
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