Spectroscopic approach of the interaction study of ceftriaxone and human serum albumin | Zendy

Teir M. M. Abu | Zendy; Jafar Ghithan | Zendy; M. I. Abu-Taha | Zendy; S. Darwish | Zendy; Mahmoud M. Abu-hadid | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Spectroscopic approach of the interaction study of ceftriaxone and human serum albumin

Author(s) -

Teir M. M. Abu,

Jafar Ghithan,

M. I. Abu-Taha,

S. Darwish,

Mahmoud M. Abu-hadid

Publication year - 2014

Publication title -

journal of biophysics and structural biology

Language(s) - English

Resource type - Journals

ISSN - 2141-2200

DOI - 10.5897/jbsb2013.0045

Subject(s) - chemistry , human serum albumin , fourier transform infrared spectroscopy , spectroscopy , binding constant , protein secondary structure , fluorescence spectroscopy , ceftriaxone , infrared spectroscopy , analytical chemistry (journal) , quenching (fluorescence) , absorption spectroscopy , fluorescence , binding site , chromatography , biochemistry , organic chemistry , antibiotics , optics , physics , quantum mechanics

-1 at 298 K. Fourier transform infrared spectroscopy (FT-IR) spectroscopy with Fourier self-deconvolution technique was used to determine the protein secondary structure and drug binding mechanisms. The observed spectral changes indicated the formation of H-bonding between ceftriaxone and HSA molecules at higher percentage for -helix than for the -sheets.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research