Anti-ulcer activity of Rhus coriaria in indomethacin and water immersion restraint induced gastric ulcer in experimental rats | Zendy

Haqeeq Ahmad | Zendy; Wadud Abdul | Zendy; Nasreen Jahan | Zendy; Hasan Izharul | Zendy

Open Access

Anti-ulcer activity of Rhus coriaria in indomethacin and water immersion restraint induced gastric ulcer in experimental rats

Author(s) -

Haqeeq Ahmad,

Wadud Abdul,

Nasreen Jahan,

Hasan Izharul

Publication year - 2015

Publication title -

international journal of medicine and medical sciences

Language(s) - English

Resource type - Journals

ISSN - 2006-9723

DOI - 10.5897/ijmms2014.1103

Subject(s) - ulcer index , medicine , traditional medicine , immersion (mathematics) , gastroenterology , drug , pharmacology , gastric mucosa , stomach , mathematics , pure mathematics

The anti-ulcer activity of hydro alcoholic extract of Rhus coriaria Linn (HAERC) was investigated in Indomethacin and Water immersion-induced restraint gastric ulcer in Wistar rats. The assessment was carried out by using ulcer index, ulcer score and histopathological studies of the specimens. HAERC at doses of 145 and 248 mg/kg given orally produced significant inhibition of the gastric lesions induced by Indomethacin and Water Immersion restraint method and the results were comparable to the standard treatment regime. We observed that Rhus coriaria Linn extract exhibits significant anti ulcer activity and thus supports the Unani claims about the drug.

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