In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium) | Zendy

B. M. Olabinri | Zendy; I. O. Fatunwase | Zendy; Patience Folashade Olabinri | Zendy

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In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium)

Author(s) -

B. M. Olabinri,

I. O. Fatunwase,

Patience Folashade Olabinri

Publication year - 2014

Publication title -

international journal of medicine and medical sciences

Language(s) - English

Resource type - Journals

ISSN - 2006-9723

DOI - 10.5897/ijmms2013.0966

Subject(s) - datura stramonium , antioxidant , flavonoid , traditional medicine , phytochemical , chemistry , saponin , tannin , chelation , nitric oxide , botany , food science , biochemistry , biology , medicine , organic chemistry , alternative medicine , pathology

This study investigated the in vitro chelating ability, antioxidant activity, total phenolic and flavonoid contents of 70% ethanolic extract of thorn apple (Datura stramonium). The ethanolic root extract of the plant displayed potent chelating ability (70%) at the lowest concentration (2%) investigated. The chelating ability of the extract showed concentration dependency. There were significant decreases in vitro chelating ability of the root extract from 2 to 10% concentrations (P 0.05) and significant from 8 to 10% (P 0.05). The ethanolic root extract failed chelate ion at the highest concentration (10%) (-20.0% activity). Key words: Phytotoxicology, clinical toxicology, iron-overload, clinical medicine, natural product.

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