Impact of seasonal malaria chemoprevention of sulphadoxinepyrimethamine plus amodiaquine on molecular markers resistance of Plasmodium falciparum malaria: A review in West Africa | Zendy

Maiga Hamma | Zendy

Open Access

Impact of seasonal malaria chemoprevention of sulphadoxinepyrimethamine plus amodiaquine on molecular markers resistance of Plasmodium falciparum malaria: A review in West Africa

Author(s) -

Maiga Hamma

Publication year - 2016

Publication title -

clinical reviews and opinions

Language(s) - English

Resource type - Journals

ISSN - 2141-2553

DOI - 10.5897/cro15.0098

Subject(s) - malaria , amodiaquine , plasmodium falciparum , drug resistance , plasmodium (life cycle) , biology , chloroquine , medicine , immunology , genetics , parasite hosting , world wide web , computer science

The study discuss the potential impact of seasonal malaria chemoprevention (SMC) on the cases of malaria, anaemia and molecular markers resistance Plasmodium falciparum malaria; and also review the mechanism of action and the effect on immunity of SMC. SMC using an efficacious drug is likely to substantially reduce cases of clinical malaria in high transmission settings. However, an increase of molecular markers could hamper rolling out SMC as a national policy. Key words: Seasonal malaria chemoprevention impact, malaria molecular markers, review.

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