Antinociceptive and healing activity of the methanolic and hydroethanolic extracts of Caulerpa taxifolia

This study aimed to evaluate the healing and analgesic action of methanolic extract and hydroalcoholic of C. taxifolia, and check the percentage of soluble proteins available in the extract of this vegetable. The collection of C. taxifolia occurred on the beach of Barra do Sirinhaem - PE, processed for testing. The animals used in the test were Swiss mice, and Mus musculus of species. For healing activity and histopathological analysis, albino rats Rattus norvegicus species, linnhagem Wistar were used. The protein content of the crude extract of C. Taxifolia has not yet been determined. The data revealed that the average displaying writhing in animal control group was 13.86. The standard group was 7.83; the group treated with hydroethanolic extract of C. taxifolia at a dose of 50 mg/kg was 8.83 and those treated with 100 mg/kg was 6.5. In the groups treated with the methanol extract of 100 mg/kg, the average value of writhing was 7.67, while 50 mg/kg resulted in 9.26 average value. It was shown that hydroethanolic and methanol extract led to early healing ofwound with epithelialized keratinized tissue and re-epithelialization; involving the restructuring of the skin appendages, during treatment and in the absence of crust.   Key words: Healing, seaweed, protein, repair.