Biological screening of ethyl acetate extract of Hedera nepalensis stem | Zendy

Ghias Uddin | Zendy

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Biological screening of ethyl acetate extract of Hedera nepalensis stem

Author(s) -

Ghias Uddin

Publication year - 2012

Publication title -

african journal of pharmacy and pharmacology

Language(s) - English

Resource type - Journals

ISSN - 1996-0816

DOI - 10.5897/ajpp12.828

Subject(s) - phytochemical , ethyl acetate , chloroform , terpenoid , traditional medicine , chemistry , antimicrobial , chromatography , organic chemistry , medicine , biochemistry

Hedera nepalensis is commonly used in folk medicines for the treatment of cough and other human ailments; therefore it was selected for phytochemical and antimicrobial screening. Its phytochemical screening showed the presence of different classes of secondary metabolites. The ethyl acetate extract of its stem showed the presence of steroids, terpenoids, saponins and flavonoids. Terpenoids and flavonoids were present in chloroform and ethyl acetate fractions, steroids were present in chloroform and ethyl acetate crude extract. Ethyl acetate and chloroform fractions were found most active. Among the organisms tested, Escherichia coli was the most sensitive to the plant extract as it displayed the greatest inhibitory zone (20:0 mm). Key words: Phytochemical screening, Hedera nepalensis, antibacterial activity.

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