Time kill-kinetics antibacterial study of Acacia nilotica | Zendy

Oladosu | Zendy; P | Zendy; 이수 | Zendy; Ibrahim A. Ibrahim | Zendy; K | Zendy; Okolo | Zendy; Oladepo | Zendy; Tushar Kumar Dey | Zendy

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Time kill-kinetics antibacterial study of Acacia nilotica

Author(s) -

Oladosu,

P,

이수,

Ibrahim A. Ibrahim,

K,

Okolo,

Oladepo,

Tushar Kumar Dey

Publication year - 2013

Publication title -

african journal of microbiology research

Language(s) - English

Resource type - Journals

ISSN - 1996-0808

DOI - 10.5897/ajmr2013.5889

Subject(s) - acacia , staphylococcus aureus , minimum inhibitory concentration , pseudomonas aeruginosa , chemistry , minimum bactericidal concentration , antibacterial activity , microbiology and biotechnology , escherichia coli , kinetics , d value , food science , bacteria , log reduction , biology , antimicrobial , botany , biochemistry , genetics , physics , quantum mechanics , gene

counts for the extract ranged between 0.18log10 and 0.35log10 cfu/ml for P. aeruginosa, 0.27log10 and 1.95log10 cfu/ml for S. aureus and 0.27log10 and 0.45log10 cfu/ml for E. coli after 10 h interaction at 0.5x MIC and 1x MIC. Most of the extracts were rapidly bactericidal at 2x MIC achieving a complete elimination of most of the test organisms within 12 h exposure. A good correlation was found between the killing curves and the MIC of A. nilotica against the test organisms.

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