Host cells response in Pseudomonas aeruginosa infections - role of quorum sensing molecules
Author(s) -
Maria Holban Alina,
Carmen Chifiriuc Mariana,
Veronica Lazăr
Publication year - 2013
Publication title -
african journal of microbiology research
Language(s) - English
Resource type - Journals
ISSN - 1996-0808
DOI - 10.5897/ajmr2013.5396
Subject(s) - quorum sensing , pseudomonas aeruginosa , virulence , immune system , pathogen , microbiology and biotechnology , cell signaling , biology , opportunistic pathogen , bacteria , signal transduction , immunology , gene , genetics
is an opportunistic Gram-negative pathogen involved in a wide spectrum of acute and chronic infections, also causing severe nosocomial complications. Among its multiple virulence determinants, the quorum sensing (QS) signaling system is used to control and coordinate the production of other virulence factors required for colonizing and persistence in different environmental conditions, but also for interfering with the host core signaling pathways. Here we review the host response mechanisms in
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