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Antimelanogenic and antioxidant activities of Bifidobacterium infantis
Author(s) -
Huang Huey Chun,
Chiu Shao Hua,
Ke Hui Ju,
Chiu Shu wen,
Wu Yun,
Chang Tsong Min
Publication year - 2011
Publication title -
african journal of microbiology research
Language(s) - English
Resource type - Journals
ISSN - 1996-0808
DOI - 10.5897/ajmr11.021
Subject(s) - abts , chemistry , melanin , tyrosinase , antioxidant , food science , skin care , cosmetics , dpph , biochemistry , organic chemistry , enzyme
The study was aimed at investigating the antimelanogenic and antioxidative effects ofBifidobacterium infantis culture filtrate. The efficacy of the bacterial culture filtrate wasevaluated spectrophotometrically. The results revealed that B. infantis culture filtrate effectively scavenge 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) ABTS radicals, and show potent reducing power in a dose-dependent pattern. Additionally, the bacterial culture filtrate suppresses murine B16F10 tyrosinase activity and the amount of melanin in a dose-dependent manner. We conclude that the B. infantis culture filtrate may be applied in the formulations of skin care cosmetics.   Key words: Bifidobacterium infantis, tyrosinase, melanin, antioxidant.

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