Effect of a cassava based diet (gari) on some renal function parameters in albino rats | Zendy

Oluseyi Adegoke | Zendy; E. Olugbenga Bamigbowu | Zendy; Maureen Ibitoroko George-Opuda | Zendy; T A Awopeju | Zendy; C.A. Mbata | Zendy; S. A. Braide | Zendy; O. V Ekwusa | Zendy; T Odunfa | Zendy

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Effect of a cassava based diet (gari) on some renal function parameters in albino rats

Author(s) -

Oluseyi Adegoke,

E. Olugbenga Bamigbowu,

Maureen Ibitoroko George-Opuda,

T A Awopeju,

C.A. Mbata,

S. A. Braide,

O. V Ekwusa,

T Odunfa

Publication year - 2015

Publication title -

african journal of cellular pathology

Language(s) - English

Resource type - Journals

eISSN - 2636-672X

pISSN - 2449-0776

DOI - 10.5897/ajcpath15.014

Subject(s) - urea , creatinine , sodium , potassium , renal function , chemistry , analysis of variance , significant difference , medicine , endocrinology , zoology , biochemistry , biology , organic chemistry

Aim: The study was carried out to ascertain the effect of Gari (a cassava based diet) on renal functions in albino rats. Methods: Thirty five Wistar albino rats divided into seven groups were fed Gari mixed with normal rat diet at concentrations of 0, 10, 20, 40, 60, 80, and 100% respectively for 3 weeks and the renal parameters (Creatinine, Urea, Sodium and Potassium) monitored in the animals. Results: There were dose dependent increases in urea, creatinine, potassium and sodium of albino rats fed Gari diet. Using analysis of variance (ANOVA), there were significant differences in the urea, and creatinine concentrations when compared to their respective controls (P 0.05). Conclusion: Therefore this study showed that Gari caused changes in renal function based on the concentration of the Gari. Keywords : Renal, Gari, Creatinine, Urea, Electrolytes

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