Correlation between glycated hemoglobin and venous blood sugar in diabetic patients monitored in Abidjan
Author(s) -
Aké Absalome MONDE,
Massara Camara-Cissé,
Konan Gervais KOFFI,
Issiagha DIALLO,
AKE Alexandre AKE,
Bénédicte YAPO-AKE,
Yann Christian Ecrabey,
Francisk Kouakou,
YAO Roger Espérance BENE,
Georges Tiahou
Publication year - 2020
Publication title -
african journal of biochemistry research
Language(s) - English
Resource type - Journals
ISSN - 1996-0778
DOI - 10.5897/ajbr2020.1102
Subject(s) - glycated hemoglobin , medicine , diabetes mellitus , hemoglobin , blood sugar , venous blood , body mass index , gastroenterology , endocrinology , type 2 diabetes
The aim of this study was to determine the correlation between glycated hemoglobin and blood sugar levels in diabetic subjects carried out in Abidjan. This cross-sectional study included 100 patients with diabetes monitored, for three months, for whom glycated blood glucose and hemoglobin were performed, this after informed consent of the patients. Pearson and Spearman correlation tests were used, at the 5% threshold. The patients with normal HbA1C and normal blood glucose accounted for 55.34 and 32%, respectively. A sedentary lifestyle and body mass index > 25 kg/m² were associated with a significant increase in the risk of increased blood glucose and HbA1C. The presence of a complication was associated with a 3.06-fold higher risk of high glycated hemoglobin (p= 0.0073), while blood glucose was not significantly associated with the onset of complications. Glycated hemoglobin was significantly correlated with blood glucose with a correlation coefficient of 0.4412 (p 0.0001). In multivariate analysis, hyperglycemia was significantly associated with alcohol consumption and non-compliance with antidiabetic treatment. Poor compliance was significantly associated with increased glycated hemoglobin (>7%) and tobacco consumption. The glycated hemoglobin was highly correlated with blood sugar, and was found to be a better predictor of diabetes complications than glycemia. Key words: Diabetes mellitus, glycated hemoglobin, blood sugar, Abidjan, Cote d’Ivoire.
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