Open AccessInvestigation of carrier oil stabilized iron oxide nanoparticles and its antibacterial activity
Author(s) -
Kun Liu,
V. Devabharathi,
Meenakshi Sundaram. N
Publication year - 2014
Publication title -
african journal of biotechnology
Language(s) - English
Resource type - Journals
ISSN - 1684-5315
DOI - 10.5897/ajb2014.13732
Subject(s) - bacillus cereus , fourier transform infrared spectroscopy , nanoparticle , iron oxide nanoparticles , iron oxide , nuclear chemistry , transmission electron microscopy , particle size , antibacterial activity , chemical engineering , oxide , chemistry , materials science , nanotechnology , bacteria , organic chemistry , genetics , engineering , biology
Iron oxide nanoparticles were synthesized by co-precipitation method. The polyunsaturated carrier oil (flaxseed oil) is used as a stabilizing agent for iron oxide nanoparticles. Kirby Bauer method was used to investigate the antibiotic sensitivity of carrier oil stabilized and uncoated SPIONs at 10 and 20 μg/L on Gram-positive bacterium Bacillus cereus (vegetative cell). The nanoparticles were characterized by X-ray diffraction method (XRD), Fourier transform infrared red (FTIR) analysis, particle size analyzer and Transmission Electron Microscopy. Structure of magnetite nanoparticles was confirmed by XRD analysis and the estimation of nanoparticle size was confirmed with TEM. The attachment of functional groups of oil was predicted using FTIR spectroscopy. This comparison study revealed that carrier oils stabilized iron oxide nanoparticles show more antibacterial activity than the bare iron oxide nanoparticles. Keywords: Iron oxide nanoparticles, flaxseed oil, Bacillus cereus African Journal of Biotechnology , Vol 13(18), 1915-1919
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